"JOURNAL OF RADIO ELECTRONICS"  N 8, 2013

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ACQUISITION OF IMAGES IN MAGNETIC RESONANCE IMAGING ON THE 19F NUCLEA WITH  THE HELP OF PREPARATION “PERFTORAN”

 

M. V. Gulyaev 1, L. L. Gervits 2, Yu. A. Ustynyuk1, N. V. Anisimov 1, Yu. A. Pirogov 1, A. R. Khokhlov 1

1 M.V.Lomonosov Moscow State University

2 A.N.Nesmeyanov Institute of Organoelement Compaunds

 

Received August 20, 2013

 

Abstract. The high magnetic moment of the nucleus 19-fluorine and its wholly-owned natural content are favorable factors for its usage in MRI. Perfluorodecalin and perftoran were used as the substances containing the nucleus 19-fluorine. These substances are biologically inert, not metabolized in living organisms and completely removed from it in an unchanged form. The scan protocols and methods of obtaining 19F-MRI images were worked out with biospectral MRI scanner. Also 1H- and 19F-MRI images of phantoms and internal organs of rats were obtained. Joint registration and processing of 1H- and 19F-MRI images significantly improves the contrast and the information content of images, increases the diagnostic value of study.

Keywords: medical physics, magnetic resonance imaging, 19F-MRI images, biospectral MRI scanner, perfluorodecalin, perftoran.