УДК
621.372.8
Изучение чувствительности клеток крови человека к микроволновому
излучению
К.
Д. Казаринов, В. А. Щелконогов, А. В. Чеканов
Фрязинский филиал Института радиотехники
и электроники им. В.А.Котельникова РАН, 141190, Московская область, г. Фрязино,
пл. академика Введенского, д. 1
Статья поступила в редакцию 21 августа 2019 г.
Аннотация. В
предлагаемой статье представлены результаты экспериментальной работы по
изучению эффектов микроволнового излучения на межклеточные взаимодействия
элементов крови человека в присутствии этанола. Микроволновое излучение низкой
интенсивности снижало активность тромбоцитов в среде этанола. Рассматривается
механизм обнаруженного эффекта, связанный с усилением апоптоза клеток.
Ключевые слова:
КВЧ излучение, обогащенная тромбоцитами
плазма, межклеточное взаимодействие, этанол, индукторы агрегации, микроволновое
излучение, алкогольная интоксикация.
Abstract. The
action of electromagnetic radiation (EMR) in the microwave range on biological
objects has been studied for more than half a century. During this time,
significant success has been achieved in the practical use of this physical
effect for therapeutic purposes. It is believed that oxidative stress, which is
a consequence of a shift in the balance of pro- and antioxidant systems, is
among the causes leading to a large number of diseases. Oxidative stress leads
to cell death, the main mechanism of which is apoptosis. Microwaves can affect
various processes associated with the development of oxidative stress. In this
work, we studied the interaction of blood cells - platelets upon irradiation
with microwaves in the presence of ethanol. Platelet activation is the cause of
vascular catastrophes, but it is not always possible to prevent the development
of complications with the help of medications. Therefore, recently in
experimental studies often proposed exposure to electromagnetic radiation in
order to correct violations of the rheological properties of blood. Such
effects include low-intensity microwave radiation. By modulating the activation
of platelets with microwave radiation, we can thereby reject various platelet
subpopulations. In addition, EHF radiation due to the effect on the water
environment and the structure of platelet membranes can accelerate the process
of adjusting the state of platelets.
Before controlling the level and
speed of platelet aggregation, they were subjected to EHF irradiation for 30
minutes. In another series of experiments, ethanol was added to the cell
incubation medium. In both cases, both a decrease in cell aggregation and a
decrease in the rate of aggregation after EHF irradiation with platelet-rich
plasma (PRP) were observed. The addition of ethanol to the PRP led to a further
decrease in the magnitude of the controlled parameters. The mechanism of the
observed effect is proposed, associated with an increase in the rate of
formation of free radicals in PRP under the influence of EHF irradiation. The
results of the research presented at VI Congress of Biophysicists of Russia and
XIV International Scientific Conference "Actual Problems of Biological
Physics and Chemistry”. The results of the work can be useful in practical medicine
for the correction of violations of the rheological properties of human blood
and, in particular, with alcohol intoxication.
Keywords: EHF radiation, platelet-rich plasma, intercellular interaction,
ethanol, aggregation inducers, microwave radiation, alcohol intoxication.
Для цитирования:
К.
Д. Казаринов, В. А. Щелконогов, А. В. Чеканов. Изучение чувствительности клеток
крови человека к микроволновому излучению. Журнал радиоэлектроники [электронный
журнал]. 2019. № 8. Режим доступа: http://jre.cplire.ru/jre/aug19/10/text.pdf
DOI 10.30898/1684-1719.2019.8.10