The study of the sensitivity of human blood cells to microwave radiation

 

K. D. Kazarinov, V. A. Shelkonogov, A. V. Chekanov

Fryazino Branch of Kotelnikov Institute of Radioengineering and Electronics of Russian Academy of Sciences,
Vvedensky Sq. 1, Fryazino Moscow region, 141120, Russia

 

The paper is received on August 21, 2019

 

Abstract. The action of electromagnetic radiation (EMR) in the microwave range on biological objects has been studied for more than half a century. During this time, significant success has been achieved in the practical use of this physical effect for therapeutic purposes. It is believed that oxidative stress, which is a consequence of a shift in the balance of pro- and antioxidant systems, is among the causes leading to a large number of diseases. Oxidative stress leads to cell death, the main mechanism of which is apoptosis. Microwaves can affect various processes associated with the development of oxidative stress. In this work, we studied the interaction of blood cells - platelets upon irradiation with microwaves in the presence of ethanol. Platelet activation is the cause of vascular catastrophes, but it is not always possible to prevent the development of complications with the help of medications. Therefore, recently in experimental studies often proposed exposure to electromagnetic radiation in order to correct violations of the rheological properties of blood. Such effects include low-intensity microwave radiation. By modulating the activation of platelets with microwave radiation, we can thereby reject various platelet subpopulations. In addition, EHF radiation due to the effect on the water environment and the structure of platelet membranes can accelerate the process of adjusting the state of platelets.

Before controlling the level and speed of platelet aggregation, they were subjected to EHF irradiation for 30 minutes. In another series of experiments, ethanol was added to the cell incubation medium. In both cases, both a decrease in cell aggregation and a decrease in the rate of aggregation after EHF irradiation with platelet-rich plasma (PRP) were observed. The addition of ethanol to the PRP led to a further decrease in the magnitude of the controlled parameters. The mechanism of the observed effect is proposed, associated with an increase in the rate of formation of free radicals in PRP under the influence of EHF irradiation.  The results of the research presented at VI Congress of Biophysicists of Russia and XIV International Scientific Conference "Actual Problems of Biological Physics and Chemistry”. The results of the work can be useful in practical medicine for the correction of violations of the rheological properties of human blood and, in particular, with alcohol intoxication. 

Keywords: EHF radiation, platelet-rich plasma, intercellular interaction, ethanol, aggregation inducers, microwave radiation, alcohol intoxication.

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For citation:

K.D. Kazarinov, V.A. Shelkonogov, A.V. Chekanov. The study of the sensitivity of human blood cells to microwave radiation. Zhurnal Radioelektroniki - Journal of Radio Electronics. 2019. No. 8. Available at http://jre.cplire.ru/jre/aug19/10/text.pdf

DOI  10.30898/1684-1719.2019.8.10