Journal of Radio Electronics. eISSN 1684-1719. 2025. ¹1

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DOI: https://doi.org/10.30898/1684-1719.2025.1.5

 

 

 

Analysis Of content of Thermal Decomposition Products

Of Urine At Prostate Cancer

And Benign Prostatic Hyperplasia

By Terahertz nonstationary Gas Spectroscopy

 

V.L. Vaks 1,2, V.A. Anfertev 1,2, E.G. Domracheva 1,2, M.B. Chernyaeva 1,2,

A.V. Maslennikova 2,3, V.A. Atduev 4, M.A. Rodionov 1,2, K.A. Atduev 4

 

1 IPM RAS, 603950, Nizhny Novgorod, GSP-105

2 Lobachevsky University, 603022, Nizhny Novgorod, Gagarina av, 23

3 Privolzhsky Research Medical University

603950, BOX-470, Nizhny Novgorod, Minin and Pozharsky square, 10/1

4 Privolzhsky District Medical Center of the Federal Medical and Biological Agency of Russia

603001, Nizhny Novgorod, Nizhnevolzhskaya quay, 2

 

The paper was received December 13, 2024.

 

Abstract. The work is devoted to studying the metabolites composition for human urine of prostate cancer and benign prostatic hyperplasia patients by terahertz (THz) high-resolution gas spectroscopy. The comparison of the composition of metabolites formed during thermal decomposition of urine of prostate cancer patients collected with preliminary prostate massage, without preliminary prostate massage and benign prostatic hyperplasia patients was carried out. The high-resolution THz spectrometer of 118-178 GHz frequency range with fast frequency sweeping developed by the authors was used. Free online spectroscopy databases were used for identification of substances. The sets of metabolites for two types of urine samples are revealed and metabolites which can be considered as potential markers of prostate cancer are determined.

Key words: high-resolution THz spectroscopy, urine, metabolites, prostate cancer, benign prostatic hyperplasia chemical composition, thermal decomposition products, absorption line.

Financing: This research was carried out under the State Assignment FFUF-2024-0024.

Corresponding author: Chernyaeva Mariya Borisovna, masha@ipmras.ru

 

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For citation:

Vaks V.L., Anfertev V.A., Domracheva E.G., Chernyaeva M.B., Maslrnnikova A.V., Atduev V.A, Rodionov M.A., Atduev K.A. Analysis of content of thermal decomposition products of urine at prostate cancer and benign prostatic hyperplasia by terahertz nonstationary gas spectroscopy // Journal of Radioelectronics. – 2025. – ¹1. https://doi.org/10.30898/1684-1719.2025.1.5 (In Russian)