"JOURNAL OF RADIO ELECTRONICS" (Zhurnal Radioelektroniki ISSN 1684-1719, N 5, 2019

contents of issue      DOI  10.30898/1684-1719.2019.5.3     full text in Russian (pdf)  



. F. Belyanin 1,2, A.S. Bagdasaryan 2,3, Yu.V. Gulyaev3 , N.S. Sergeeva 4, S.A. Bagdasaryan 1,2, E.R. Pavlyukova 3 

1 Central Research Technological Institute Technomash, 4, Ivan Franko Str., Moscow 121108, Russia

2 Scientific Engineering Center Technological developments of telecommunication and radio frequency identification, JSC, 4 (1), Sukharevskaya Sq., Moscow 127051, Russia

3 Kotelnikov Institute of Radio-engineering and Electronics RAS, 11 (7), Mokhovaya Str., Moscow 125009, Russia

4 Herzen Moscow Oncology Research Center, National Medical Research Radiological Center, Ministry of Health RF, 3, 2nd Botkinskiy Proyezd, Moscow 125284, Russia


The paper is received on May 6, 2019


Abstract. The key problems for creation of bioartificial organs and tissues are the development of frame matrixes (carriers) for cells using nanoparticles of the different materials. To develop the adequate hybrid structures it is necessary to study the interaction of synthetic opal matrixes and natural analogues of similar materials, in particular, geyserite with cellular systems in order to create biocompatible materials for reconstructive plastic surgery. In the presented article the possibility to obtain and apply biocompatible opal matrixes (natural and artificial) for the cultivation of cellular systems, including multipotent mesenchymal stromal cells (MMSC): namely, the features of the formation and composition for "opal matrix (geyserite) - cell culture" type structure are considered. Investigation of biocompatibility for microparticles of opal matrixes in vivo was made for the following sample sample: fraction of opal matrix particles <40 m, treatment temperature 790C). The best matrix properties were demobnstrated in experiments. Executed investigations confirm the biocompatibility of opal matrixes (synthetic and natural) in a shape-shifter for biologically inert materials and the application in regenerative medicine.

Keywords: opal matrices, nanocomposites, multipotent mesenchymal stromal cells (MMSC).


1. M.I. Samoilovich, S.M. Klescheva, A.F. Belyanin, V.D.Zhitkovsky, M.Yu.Tsvetkov. Three-dimensional nanocomposites based on ordered packs of silica nanospheres. Part 1-3. Mikrosistemnaya tekhnika - Microsystem technology. 2004. No. 6, p.3-7. No. 7, C.2-11. No. 8, pp. 917. (In Russian)

2. V.S. Urusov, L.V.Shvanskaya, A.Yu.Bychkov, A.V. Mokhov, E.A.Labutova. Microstructure investigations of Kamchatka geyserites. Moscow University Geology Bulletin. 2008. Vol. 63. No. 5. pp. 311-319. DOI 10.3103/S0145875208050037

3. F.Inagaki, Y.Motomura, S.Ogata. Microbial silica deposition in geothermal hot waters. Appl. Microbiol. Biotechnol. 2003. Vol. 60. pp. 605611.

4. M.I.Samoilovich, N.S.Sergeeva, A.F.Belyanin, I.K.Sviridova, V.D.Zhitkovskiy. Peculiarities of interection of opal matrices based on cubic packings of SiO2 nanospheres with cellular structures. Stem cells: policy, research and innovations. European Union Russian Federation perspectives. British-Russian Workshop in association with the European commission. 2007. Moscow, British council. pp. 3335.

5. Bagdasaryan A.S., Bagdasaryan S.A., Belyanin A.F., Kaschenko O.V., Pavlyukova E.R. Information technologies for the implementation of a patient-oriented approach in the management system of the therapeutic and diagnostic process in patients with arterial hypertension. Report at the VI Interdisciplinary Congress on diseases of the head and neck organs. Moscow, Burdenko NMIC Neurosurgery. May 17, 2018 (In Russian)

6. Bagdasaryan A.S., Bagdasaryan S.A. Information technologies using radio monitoring in general medical practice. Fundamentalnye problem radioelektronnogo priborostroeniya - Fundamental problems of radio-electronic instrument making. 2018. Vol. 18. No. 3. pp. 521-525. (In Russian)

7. Bagdasaryan A.S., Gulyaev Yu.V., Kalyaev I.A., Bagdasaryan S.A., Korobkin V.V. Intellectual devices on surfactants for nuclear energy: new developments and achievements. Proceedings of the International Scientific and Practical Conference Alternativnaya i intellektualnaya energetika [Alternative and intellectual energy]. Voronezh, Voronezh State Technical University, 2018. pp. 60-62. Available at http://aie.cchgeu.ru/upload/staff/upr-nauki-i-innov/konf-aie/%20%20-%20%20%20%20%20.pdf (In Russian)

8. A.S. Bagdasaryan, V.V. Butenko Telecommunications medium in the epoxy of the information society: Intellectual devices and materials of the functional electronics. Proceedings of II International Scientific-Technical and Scientific-Methodical Conference Aktualnye problemy infotelekommunikatsiy v nauke I obrazovanii (APINO 2019) [Actual Problems of Information Telecommunications in Science and Education (APINO 2019)]. St. Petersburg, 27 - 28 February 2019. Available at https://niir.ru/wp-content/uploads/2019/02/C-.pdf (In Russian)

9. A.S. Bagdasaryan, S.A.Bagdasaryan, A.F. Suggested methods and approaches. Proceedings of the conference Infomatika i tekhnilogii. Innovatsionnye tekhnologii v promyshlennsti i informatike (RNTK FTI-2019) [Informatics and technology. Innovative technologies in industry and computer science (RNTK PTI- 2019)]. Moscow, April 11 - 12, 2019. Physics and Technology Institute MIREA. Available at https://niir.ru/wp-content/uploads/2019/04/--.pdf  (In Russian)


For citation:
.F.Belyanin, A.S.Bagdasaryan, Yu.V.Gulyaev, N.S.Sergeeva, S.A.Bagdasaryan, E.R.Pavlyukova. Biocompatible nano materials based on opal matrixes. Zhurnal Radioelektroniki - Journal of Radio Electronics. 2019. No. 5. Available at http://jre.cplire.ru/jre/may19/3/text.pdf