"JOURNAL OF RADIO ELECTRONICS" (Zhurnal Radioelektroniki ISSN 1684-1719, N 10, 2018

contents of issue      DOI  10.30898/1684-1719.2018.10.13     full text in Russian (pdf)  

Studies of the surface properties of lipid monolayers as models of biological membranes


S. V. Titov 1, V. S. Malinin 1, A. S. Titov 2, K. D. Kazarinov 1

1 Fryazino Branch of Kotelnikov Institute of Radioengineering and Electronics of Russian Academy of Sciences,
Vvedensky Sq.1, Fryazino Moscow region 141190, Russia

2 Moscow Institute of Physics and Technology (State University),
 9 Institutskiy per., Dolgoprudny, Moscow Region, 141701, Russian Federation


The paper is received on October 9, 2018


Abstract. A method of investigation of the surface properties of lipid monolayers for the study of microwave biological effects is developed. The solution of the Navier-Stokes equation, describing the propagation of surface waves of a liquid as applied to lipid monolayers, permits the determination of the surface tension and viscosity of a monolayer as a function of the excitation frequency, the wave vector and the attenuation coefficient of the surface wave. The analysis of the effect of lipid monolayers on the propagation of surface waves is presented. It is shown that the presence of a lipid film on the surface of a liquid changes the wavelength of capillary waves and the attenuation coefficient for a fixed excitation frequency. One advantage of the method is that an ac electric field is used to generate surface waves which when combined with optical measurement renders this technique absolutely contact free. The results so obtained can serve as a basis for subsequent experiments applying electrostriction generation of capillary waves to the study of the surface properties of lipid monolayers as affected by microwave radiation.

Key words: biological effects of microwave radiation, generation of surface waves, surfactants, lipid monolayers, models of biological membranes, wavelength and attenuation of surface waves, Navier-Stokes equation.


1.   Kazarinov K.D. Biological effects from UHFradiation of low intensity. Itogi nauki I tehniki - Advances of science and technology, Series «Biophysics», Ì. VINITI. 1990. Vol.27. 102 p. (In Russian).

2.   Eidy R. Electromagnetic interactions on cell membranes: stereotype rearrangement. In: XII Sechenov Readings. Ìoscow, Russian Academy of Sciences, Russian Academy of Medical Sciences. 1996. pp. 3-21. (In Russian).

3.   Kazarinov K.D. The study of membranotropic activity of electromagnetic radiation in a wide range of wavelengths. Elektronnaya tehnikaElectronic technique, Ser. 1. VHF-technique, 2018. No. 2 (537). pp. 62-75. Available at: http://www.istokmw.ru/uploads/files/static/101/UHF2018-2.pdf (In Russian).

4.   Davies J.T., Redial Å.Ê. Interfacial phenomena. London. Academic Press. 1963. 480 p. Available at: https://trove.nla.gov.au/work/18699052?selectedversion=NBD2936621

5.   Jaycock M. J. and Parfitt G. D. Chemistry of Interfaces. New York. Halstead Press. John Wiley and Sons. 1981. 279 p. DOI: 10.1080/01932698208943653

6.   Shih L.B. Surface fluctuation spectroscopy: a novel technique for characterizing liquid interfaces. Rev. Sci. Instrum. 1984. Vol. 55. pp.716-726. DOI: 10.1063/1.1137825

7.   Maloy K.J., Feder J., Jossang T. An experimental technique for measurements of capillary waves. Rev. Sci. Instrum. 1998. Vol. 60. pp. 481-486. DOI: 10.1063/1.1140403

8.   Jackson J.D. Classical Electrodynamics. New York. John Wiley & Sons. 1962. 641 p. DOI: 10.1063/1.3057859

9.   Sohl C.H., Miyano Κ., Ketterson J.B. Novel technique for dynamic surface tension and viscosity measurements at liquid-gas interfaces. Rev. Sci. Instrum. 2008. Vol. 49. pp. 1464-1469. DOI: 10.1063/1.1135288

10. Malinin V.S., Polnikov I.G., Kazarinov K.D. Method of electrostriction generation of capillary waves in studying surface properties of lipid monolayers. VI International Congress, Saint Petersburg, 02 - 06 July 2012, Congress Proceedings: Symposium A, P.122.  Available at: www.biophys.ru/archive/congress2012/proc-p122.htm (In Russian).

11. Sedov L.I. Mehanika sploshnyh sred [Continuum Mechanics]. Ìoscow, Nauka Publ., 1970.  Vol. 1.  492 p. (In Russian).

12. Levich V.G. Fisiko-himicheskaya gidrodinamika [Physical-chemical hydrodynamics]. Ìoscow, Fisiko-matematicheskaya literature Publ., 1959. 699 p. (In Russian).

13. Yu S.H., Possmayer F., Adsorption, Compression and Stability of Surface Films from Natural, Lipid Extract and Reconstituted Pulmonary Surfactants. Biochim. Biophys. Acta. 1993. Vol. 1167. pp. 264-271. Available at: https://www.ncbi.nlm.nih.gov/pubmed/8481387 (In Russian).

14. Berezovskii V.A., Gorchakov V.Yu. Poverhnostno-aktivnye veschestva legkogo [Surface-active substances of the lung]. Kiev, Naukova Dumka Publ., 1982. 168 p. (In Russian).

15. Rozenberg O.A. Pulmonary surfactant and its use in lung diseases.  Obschaya reanimatologiya - General resuscitation, 2007. Vol. 3, No 1. pp. 66-77. DOI: 10.15360/1813-9779-2007-1-66-77 (In Russian).

16. Kazarinov K.D., Gorodetskaya M.V., Polnikov I.G. Application of the waveguide dielectric method for monitoring and research of highly absorbing liquids in the microwave range. Elektronnaya tehnikaElectronic technique, Ser. 1. VHF-technique, 2014. No 1 (520).  pp. 82-94. Available at: https://elibrary.ru/item.asp?id=27519244 (In Russian).

17. Kazarinov K.D. The role of cell membrane systems in the reception of electromagnetic fields of the UHF-range by biological objects. Elektronnaya tehnikaElectronic technique, Ser. 1. VHF-technique, 2008. No 1. pp.42-55. Available at: https://elibrary.ru/item.asp?id=11655805 (In Russian).


For citation:

S. V. Titov, V. S. Malinin, A. S. Titov, K. D. Kazarinov. Studies of the surface properties of lipid monolayers as models of biological membranes. Zhurnal Radioelektroniki - Journal of Radio Electronics. 2018. No. 10. Available at http://jre.cplire.ru/jre/oct18/13/text.pdf

DOI  10.30898/1684-1719.2018.10.13