High precise THz spectroscopy forsolutions of medical and biology problems
V. L.Vaks
1,2, E. G.
Domracheva 1,2, E.
A.Sobakinskaya 1,2,
M. B.Chernyaeva
1,2, V. A.Anfert’ev
1,2, A.V.Semenova
1,2, Yu. S.
Shatrova1,2
1Institute for
Physics of Microstructures of RAS
2Lobachevsky State
University of Nizhny Novgorod
The paper is received
on January 21, 2014
Abstract: One of the most prospective methods of non-invasive diagnostics is the
exhaled breath analysis which can be used not only for detecting various
diseases and prediction of organism response on concrete medical treatment, but
also for monitoring of therapy efficiency. Based on the measuring of
gas-markers concentration one can diagnose a number of serious diseases
including gastrointestinal, oncological, neuropsychic and ENT diseases. Among
the variety of methods of exhaled breath analysis the most prospective are the
spectroscopic ones, and namely terahertz spectroscopy. The undoubted advantages of terahertz gas spectroscopy are the high
sensitivity and resolution simultaneously. In the paper the results of exhaled
breath spectroscopic investigations with using the THz spectrometers developed
for non-invasive medical diagnostics of diabetes, pre-cancer states and
oncological diseases of gastrointestinal tract, as well as for monitoring the
efficiency of radiotherapy on dynamics of ÒÙ concentration are presented. The fine structure of DNA
spectrum in the frequency range of 300-375 GHz with using the high-precision
spectrometer based on BWO frequency synthesizer and high quality resonator was
studied.
Key words: terahertz frequency range, high precise
non-stationary spectroscopy, non-invasive medical diagnostics, exhaled breath,
gas-marker.
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